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Influenza: The Hundred Year Hunt to Cure the Deadliest Disease in History
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Review
“The influenza pandemic of 1918 was responsible for an estimated 50–100 million deaths worldwide. A century later, ‘The flu is still a serial killer,’ writes emergency-medicine physician Brown... Brown smartly examines this viral infection from all sorts of angles—medical history, virology, diagnosis and treatment, economics and epidemiology‚ health-care policy, and prevention.” —Starred Booklist “Influenza tells a surprisingly compelling and accessible story of one of the world's most deadly diseases. It is timely and interesting, engaging and sobering.” —David Gregory, CNN Political Analyst and former moderator for NBC’s, Meet the Press“Jeremy Brown, one of the country's leading emergency physicians, has written a terrific book. From the Great Influenza Pandemic of 1918 to our most recent outbreaks, he tells a gripping story that brings an entirely new perspective on our battle against influenza. Extensively researched and often humorous, it reminds us of the great strides modern medicine has made, and of the dangers that we still face each flu season.” —Gail D’Onofrio MD, Professor and Chair, Department of Emergency Medicine, Yale School of Medicine“Even now, a century after the great flu pandemic of 1918, which left an estimated 50 to 100 million people dead worldwide, there's still no cure, writes Brown, an ER veteran and director of the National Institutes of Health's Office of Emergency Care Research. In his debut, he traces the millions-of-years history of the virus, efforts to understand and treat it, and its many devastating outbreaks… A solid book of popular science.” —Kirkus Reviews“Brown, director of the Office of Emergency Care Research at the National Institutes of Health, marks the 100th anniversary of the 1918 Spanish flu pandemic with this no-nonsense account of medicine’s long battle against influenza. Brown recounts the ‘epic effort’ in the 1990s to resurrect and genetically decode the Spanish flu, which, in addition to triggering concern that “all this tinkering was creating superviruses,” underscored influenza’s elusiveness. As an experienced ER doctor, he also offers plain advice on dealing with the virus.”—Publishers Weekly"A thoughtful portrait of an elusive enemy.” —Nature.com“An in-depth look at what scientists know now about the 1918 strain [and] a fascinating look at the factors that make the more common seasonal flu so challenging to predict and prevent… For those who want more science with a frank discussion of the challenges influenza still poses, Brown delivers a clear and captivating overview.” —Science News
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About the Author
Dr. Jeremy Brown trained at University College School of Medicine in London and completed his residency in emergency medicine in Boston. He was the Research Director in the Department of Emergency Medicine at George Washington University before moving to the National Institutes of Health, where he now directs its Office of Emergency Care Research. His opinion pieces have been published in The New York Times and The Washington Post, and he has written for Discover magazine.
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Product details
Hardcover: 272 pages
Publisher: Atria Books (December 18, 2018)
Language: English
ISBN-10: 1501181246
ISBN-13: 978-1501181245
Product Dimensions:
6 x 0.9 x 9 inches
Shipping Weight: 14.9 ounces (View shipping rates and policies)
Average Customer Review:
4.7 out of 5 stars
14 customer reviews
Amazon Best Sellers Rank:
#43,218 in Books (See Top 100 in Books)
Jeremy Brown has written an intelligent, engaging and very well-written book about an issue that is both historic and (alarmingly) contemporary. He has a very easy writing style, with occasional irreverently humorous comments. (Little has changed since I taught him in HIgh School some 40 years ago.... the cleverest student I ever had.). Most of all, he has a great curiosity about the world, which shows through clearly in this book, and - a rare, precious quality for a writer - communicates itself to the reader, who is drawn into the topic. If you enjoy medical / scientific/ sociological ‘whodunnits’, you will love this book - a great read, and a great gift!It should be mentioned that he is an amazingly diverse polymath, who glides from arcane subject (Emergency Medicine, Medieval science, the history of ideas, obscure rabbinic texts) to arcane subject. Keep writing, please - the best is yet to come!
A Wellwritten, accessible to non medical people account of the 1918 flu outbreak, along with current theories about the cause and what is being done today in case of another killer pandemic.
Provides a good concise history of the influenza Pandemic of 1918 and ties it into the common issues facing today with clinic. Interesting take on vaccines, antiviral therapy and controversy with the Tamilflu. Good up to date info.
Most people are aware of the epidemic of Spanish flu that killed millions worldwide in 1918. Now a hundred years have passed, and the best information we have, according to research physician Jerry Brown, indicates that we are not much closer to finding a cure for the flu, or predicting and coping with a massive outbreak, than we were a century ago.Beginning with a harrowing story of a modern flu victim to illustrate how devastating “just the flu†can still be, Brown then takes us back to 1918, when two wars were being waged: World War I and the fight against the flu. The latter was especially significant since conditions for the disease’s spread were ideal: the virus needs live cells to do its dirty work, and to find live cells it needs crowds. Those in uniform in crowded barracks were susceptible, along with the poor, crammed into tenements with many family members occupying a tiny space. Add to that the virus’s “shapeshifting†capabilities, which explain why we may get the flu more than once in a season (usually, Brown says, a winter period of low to no sunlight).In 1918, people, including medical providers, relied on ineffective or fatal remedies such as bloodletting, gas inhalation and overdosing on aspirin. A disturbing chart offered by Brown depicts the average life expectancy in 1918 --- around 40 --- as compared to the pre-1918 flu rate of 55 and the gradual rise to 70 by 1960.Yet, as Brown points out, some survive the flu. But despite studies that have included such extremes as digging up the frozen bodies of flu victims in Alaska and elsewhere, little is known about how to stop the virus from jumping off birds and swine and hopping onto people. It still kills about 30,000 Americans each year.Brown, the Director of Emergency Care Research at the National Institutes of Health, avers that there is still no drug that eradicates the virus, and added to the problem are anti-viral drugs that are efficacious at creating controversy, as none seems to work, or to work every year, or in all cases. Brown believes that by forgetting the ravages of the 1918 epidemic, we may be doomed to have a repeat: “Marking its centennial is a step in the right direction, but it’s a very small step.†He’s calling for a 1918 "flu memorial" and hopes that by the time it’s built, “we will also be celebrating a cure.â€Reviewed by Barbara Bamberger Scott
investigation, medical, historical-research, historical-places-events, historical-figures, pandemicI'm not certain who will benefit most from this book. The very beginning could be quite off putting to the general public while paramedicals like me are entranced. Lots of it is easily comprehensible to most, while some sections might make some folks glassy eyed. Yet you ask why I recommend it to everyone.Simple. Historians, research minded, descendants, patients, and those in paramedical fields will benefit from the research and perspectives laid out in this book. Whether you want to know how influenza traveled, why this particular strain is not freely active, how vaccines are developed, what treatments were used throughout history for the illness and if/when some were finally discarded, and just why the grandmothers were right about dosing with chicken soup, you will find your answers here.I had the grandest time reading this one, and I have read a number of others, because of the logical way that sections are organized as well as some areas having a slightly different perspective than some others. I hope that many others will at least learn a lot from it.I requested and received a free ebook copy from Touchstone/Simon and Schuster Publishing via NetGalley. Thank you!
Influenza by Dr. Jeremy Brown2018 is the 100th anniversary of the Influenza pandemic of 1918 that killed 50 to 100 million people worldwide and infected as many as a third of the world’s population. Dr. Brown not only documents the events of 1918 but more importantly explores research and breakthroughs in the field since then. With this added knowledge, he lets the reader ponder whether another pandemic is likely to happen again, and if so, how deadly would it be. Surprisingly, medicine may not have progressed as far as most of us would like to think. Dr. Jeremy Brown, director of Emergency Care Research at the National Institutes of Health, along with his exhaustive research is well qualified to tell us this story.In documenting the history of the disease, “Influenza†covers many interesting stories including the need to recover the bodies of 1918 influenza victims that remained frozen in the Alaskan tundra since their death. Brown also delves into the economic and social impact of flu and today's fight against the virus and the immunizations that remain controversial to this day.Much has been written about the 1918 pandemic but this book goes beyond the story of 1918. It follows the disease for a century and documents our fight against it.
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